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Williams JA, Hathcock KS, Klug D, Harada Y, Choudhury B, Allison JP, Abe R, Hodes RJ. (2005) Regulated costimulation in the thymus is critical for T cell development: dysregulated CD28 costimulation can bypass the pre-TCR checkpoint. J. Immunol. 175:4199-4207 >>>Go to PubMed >>>Full Text Watanabe M, Watanabe S, Hara Y, Harada Y, Kubo M, Tanabe K, Toma H, Abe R. (2005) ICOS-mediated costimulation on Th2 differentiation is achieved by the enhancement of IL-4 receptor-mediated signaling. J. Immunol. 174:1989-1996 >>>Go to PubMed >>>Full Text Sanchez-Lockhart, M., Marin, E., Graf, B., Abe, R., Harada, Y, Sedwick, CE., Miller, J. (2004) Cutting Edge: CD28-Mediated Transcriptional and Posttranscriptional Regulation of IL-2 Expression Are Controlled through Different Signaling Pathways. J. Immunol. 173:7120-7124 >>>Go to PubMed >>>Full Text Tokoyoda, K., Tsujikawa, K., Matsushita, H., Ono, Y., Hayashi, T., Harada, Y, Abe, R., Kubo, M., Yamamoto, H. (2004) Up-regulation of IL-4 production by the activated cAMP/cAMP-dependent protein kinase (protein kinase A) pathway in CD3/CD28-stimulated naive T cells. Int. Immunol. 16:643-653 >>>Go to PubMed >>>Full Text Matsumoto, A., Seki, Y., Watanabe, R., Hayashi, K., Johnston, JA., Harada, Y, Abe, R., Yoshimura, A., Kubo, M. (2003) A role of suppressor of cytokine signaling 3 (SOCS3/CIS3/SSI3) in CD28-mediated interleukin 2 production. J. Exp. Med. 197:425-436 >>>Go to PubMed >>>Full Text Harada, Y, Ohgai, D., Watanabe, R., Okano, K., Koiwai, O., Tanabe, K., Toma, H., Altman, A., Abe, R. (2003) A single amino acid alteration in cytoplasmic domain determines IL-2 promoter activation by ligation of CD28 but not inducible costimulator(ICOS). J. Exp. Med. 197:257-262 >>>Go to PubMed >>>Full Text Harada Y, Tokushima M, Matsumoto Y, Ogawa S, Otsuka M, Hayashi K, June CH, Abe R. (2001) Critical requirement for the membrane proximal cytosolic tyroinse residue for CD28 mediated costimulation in vivo. J. Immunol. 166:3797-3803 >>>Go to PubMed >>>Full Text Harada, Y, Tanabe, E., Watanabe, R., Weiss, B.D., Matsumoto, A., Ariga, H., Koiwai, O.,Fukui, Y., Kubo, M., June, C.H., and Abe, R. (2001). Novel role of PI3-K in CD28-mediated costimulation. J. Biol. Chem. 276:9003-9008 >>>Go to PubMed Maita, H., Harada, Y, Nagakubo, D., Kitaura, H., Ikeda, M., Tamai, K., Takahashi, K., Ariga, H., and Iguchi-Ariga, S. M. (2000). PAP-1, a novel target protein of phosphorylation by pim-1. Eur. J. Biochem. 267, 5168-78. >>>Go to PubMed >>>Full Text Takahashi, C., Harada, Y, Ariga, H., and Iguchi-Ariga, S. M. (1995). Involvement of PIM-1 in DNA fragmentation in mouse NS-1-derived cells. Biochem. Biophys. Res. Commun. 215, 538-46. >>>Go to PubMed >>>Full Text >> 久保 允人 2014 2013 2012 2011 2010 2009 2008 2007 >> 原田 陽介 2006-2013 1995-2005 >> 大谷 真志 2004-2013
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