>> 久保 允人 2014 2013 2012 2011 2010 2009 2008 2007        
>> 原田 陽介 2006-2013 1995-2005  

>> 大谷 真志 2004-2013   

原田 陽介 2006-2012

<英文論文>
Harada Y, Tanaka, S., Harada, Y., Motomura, Y., Ohno, S., Ohno, S., Yanagi, Y., Hiromasa Inoue, H.,and Kubo, M ; The 3 Enhancer CNS2 Is a Critical Regulator of Interleukin-4-Mediated Humoral Immunity in Follicular Helper T Cells. Immunity 36, (2), 188-200, 24 February 2012 >>>Go to PubMed >>>>Full Text

Harada Y, Harada Y, Elly C, Ying G, Paik JH, DePinho RA, Liu YC.Transcription factors Foxo3a and Foxo1 couple the E3 ligase Cbl-b to the induction of Foxp3 expression in induced regulatory T cells. J Exp Med. 2010 Jul 5;207(7):1381-91 >>>>Go to PubMed >>>>Full Text

Kojo S, Elly C, Harada Y, Langdon WY, Kronenberg M, Liu YC. Mechanisms of NKT cell anergy induction involve Cbl-b-promoted monoubiquitination of CARMA1. Proc. Natl. Acad. Sci. USA, 106:17847-17851 >>>Go to PubMed >>>Full Text

Hundt M, Harada Y, De Giorgio L, Tanimura N, Zhang W, and Altman A. Palmitoylation-dependent plasma membrane transport, but lipid raftindependentsignaling by linker for activation of T cells (LAT). J. Immunol., 183:1685-1694 >>>Go to PubMed >>>Full Text

Takeda K*, Harada Y*, Watanabe R, Inutake Y, Ogawa S, Onuki K, Kagaya S, Tanabe K, Kishimoto H, Abe R. (2008) CD28 stimulation triggers NF-kappaB activation through the CARMA1-PKCtheta-Grb2/Gads axis. Int. Immunol. 20:1507-1515 (*equal contributors) >>>Go to PubMed >>>Full Text

Venuprasad K, Huang H, Harada Y, Elly C, Subramaniam M, Spelsberg T, Su J, Liu YC. (2008) The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1. Nat. Immunol. 9:245-253 >>>Go to PubMed >>>Full Text

Watanabe R*, Harada Y*, Takeda K*, Takahashi J, Ohnuki K, Ogawa S, Ohgai D, Kaibara N, Koiwai O, Tanabe K, Toma H, Sugamura K, Abe R. (2006) Grb2 and Gads exhibit different interactions with CD28 and play distinct roles in CD28-mediated costimulation. J. Immunol. 177:1085-1091 (*equal contributors) >>>Go to PubMed >>>Full Text

Venuprasad K, Yang C, Shao Y, Demydenko D, Harada Y, Jeon MS, Liu YC. (2006) Immune regulation by ubiquitin conjugation. Adv. Exp. Med. Biol. 584:207-217 >>>Go to PubMed

Venuprasad K, Elly C, Gao M, Salek-Ardakani S, Harada Y, Luo JL, Yang C, Croft M, Inoue K, Karin M, Liu YC. (2006) Convergence of Itch-induced ubiquitination with MEKK1-JNK signaling in Th2 tolerance and airway inflammation. J. Clin. Invest. 116:1117-26 >>>Go to PubMed >>>Full Text

Yang C, Zhou W, Jeon MS, Demydenko D, Harada Y, Zhou H, Liu YC. (2006) Negative regulation of the E3 ubiquitin ligase itch via Fyn-mediated tyrosine phosphorylation. Mol. Cell. 21:135-141 >>>Go to PubMed >>>Full Text

<邦文著作>
原田陽介・久保允人: 胸腺内でのT細胞分化とサイトカイン 増刊号 「サイトカインのすべて」 臨床免疫・アレルギー科 Vol.57 Suppl.21, p664-669, 2012

原田陽介・久保允人「CNS2エンハンサーは濾胞性ヘルパーT細胞によるインターロイキン4に依存性の液性免疫応答を制御する」 「新着論文レビュー」 ライフサイエンス統合データベースセンター
http://first.lifesciencedb.jp/archives/4596#more-4596


>> 久保 允人 2014 2013 2012 2011 2010 2009 2008 2007        
>> 原田 陽介 2006-2013 1995-2005  

>> 大谷 真志 2004-2013  
 

 

 

 
東京理科大学生命科学研究所
東京理科大学
理化学研究所 免疫アレルギー科学総合研究センター
大学院生・卒研生募集
コピーライト
トップページ お問合せ