PD：Chandrasekar Balachandran of New Site 0

メール　アドレス：balaeri09@gmail.com（＠は半角に直してください）

Entomology Research Institute, University of Madras, Chennai, India
Ph.D., Biomedical Science, 2011/12 - 2015/03
Supervisors: 1) Prof. Savarimuthu Ignacimuthu and 2) Asso. Prof. Veeramuthu Duraipandiyan

Department of Biomedical Science, Loyola College, University of Madras, Chennai, India
M.S., Biomedical Science, 2007/06 – 2009/03

Department of Plant Biology and Plant Biotechnology, PSG College of Arts and Science, Bharathiar University, Coimbatore, India
B.S., Plant Biology and Plant Biotechnology 2001/07 – 2005/12

Postdoctoral Research Fellow
Faculty of Pharmaceutical Sciences, Tokyo University of Science, Chiba, Japan. 2018/04 – 2019/03. Advisor: Prof. Shin Aoki

Postdoctoral Research Fellow
Institute of Natural Medicine, University of Toyama, Japan. 2016/ 11 – 2018/ 03
Advisor: Asso. Prof. Suresh Awale

Postdoctoral Research Fellow
Department of Hematology, Fujita Health University, Japan. 2015/ 04 – 2016/ 10
Advisor: Prof. Nobuhiko Emi

Senior Research Fellow
Entomology Research Institute, University of Madras, Chennai, India. 2010/ 09 – 2012/ 08
Advisor: Prof. Savarimuthu Ignacimuthu

1. Kana Naito, Kenta Yokoi, C. Balachandran, Yosuke Hisamatsu, Shin Aoki. Design, Synthesis, and Anticancer Activity of Iridium(III) Complex-Peptide Hybrids that Contain Hydrophobic Acyl Groups at the N-Terminus of the Peptide Units. Journal of Inorganic Biochemistry, 2019, 199, 110785. (IF: 3.224 in 2018)
2. Nithya Murugesh, Jebiti Haribabu, Krishnamoorthy Arumugam, C. Balachandran, Rajagopal Swaathy, Shin Aoki, Anandaram Sreekanth, Ramasamy Karvembu, Seenuvasan Vedachalam. NHC catalyzed green synthesis of functionalized chromones: DFT mechanistic insights and in vitro activities in cancer cells. RSC New Journal of Chemistry, 2019, 43, 13509. (IF: 3.069 in 2018)
3. Mathiyan Muralisankar, Ramachandran Dheepika, Jebiti Haribabu, C. Balachandran, Shin Aoki, Nattami S. P. Bhuvanesh, Samuthira Nagarajan. Design, synthesis, DNA/HSA binding and cytotoxic activity of half-sandwich Ru(II)-arene complexes containing triarylamines- thiose micarbazone hybrids. ACS Omega, 2019, 4, 11712−11723. (IF: 2.584 in 2018)
4. Kumaramangalam Jeyalakshmi, Jebiti Haribabu, C. Balachandran, Eswaramoorthi Narmatha, Nattamai S. P. Bhuvanesh, Shin Aoki, and Ramasamy Karvembu. Highly Active Copper(I) Complexes of Aroylthiourea Ligands Against Cancer Cells – Synthetic and Biological Studies. RSC New Journal of Chemistry, 2019, 43, 3188. (IF: 3.069 in 2018)
5. Kaliyappan Easwaramoorthi, Jeya A. Rajendran, Kella Chennakesava Rao, C. Balachandran, Yuvaraj Arun, Sakkarapalayam M. Mahalingam, Natarajan Arumugam, Abdulrahman I. Almansour, Raju Suresh Kumar, Dhaifallah M. Al-thamili, Shin Aoki. A New Class of β–Pyrrolidino-1,2,3-Triazole Derivatives as β-Adrenergic Receptor Inhibitors: Synthesis, Pharmacological, and Docking Studies. Molecules, 2019, 24, 3501 (IF: 3.06 in 2018)
6. K. Jeyalakshmi, J. Haribabu, C. Balachandran, S. Srividya, N. Bhuvanesh, R. Karvembu. Coordination Behavior of N,N′,N″‑ Trisubstituted Guanidine Ligands in Their Ru−Arene Complexes: Synthetic, DNA/Protein Binding, and Cytotoxic Studies. ACS Organometallics, 2019, 38, 753−770. (IF: 4.1 in 2018)
7. C. Balachandran, J. Haribabu, K. Jeyalakshmi, Nattamai S.P. Bhuvanesh, R. Karvembu, N. Emi, S. Awale. Nickel(II) bis(isatinthiosemicarbazone) complexes-induced apoptosis through mitochondrial signaling pathway and G0/G1 cell cycle arrest in IM-9 cells. Journal of Inorganic Biochemistry, 2018, 182, 208–221. (IF: 3.224 in 2018)
8. J. Haribabu, G. Sabapathi, M. M. Tamizh, C. Balachandran, N. S. P. Bhuvanesh, P. Venuvanalingam and R. Karvembu. Water soluble mono- and binuclear Ru(6-p-cymene) complexes containing indole thiosemicarbazones: Synthesis, DFT modeling, biomolecular interactions and in vitro anticancer activity through apoptosis. ACS Organometallics, 2018, 1242–1257. (IF: 4.1 in 2018)
9. T. Thirunavukkarasu, H. A. Sparkes, C. Balachandran, S. Awale, K. Natarajan. Bis(μ-chloro) bridged 1D CuI and CuII coordination polymer complex and mononuclear CuII complex: Synthesis, crystal structure and biological properties. Journal of Photochemistry and Photobiology B: Biology, 2018, 181, 59–69. (IF: 4.067 in 2017)
10. S. Awale, D. F. Dibwe, C. Balachandran, S. Fayez, J. Li, D. Feineis, B.K. Lombe, G. Bringmann. Ancistrolikokine E3, a 5,8-Coupled Naphthylisoquinoline Alkaloid, Eliminates the Tolerance of Cancer Cells to Nutrition Starvation by Inhibition of the Akt/mTOR/Autophagy Signaling Pathway. Journal of Natural Products, 2018, 2282–2291. (IF: 4.257 in 2018)
11. S. Sun, A. Phrutivorapongkul, D. F. Dibwe, C. Balachandran, S. Awale. Chemical constituents of Thai Citrus hystrix and their antiausterity activity against the PANC-1 human pancreatic cancer cell line. Journal of Natural Products, 2018, 1877−1883. (IF: 4.257 in 2018)
12. J. Haribabu, M. M. Tamizh, C. Balachandran, Y. Arun, N. S. P. Bhuvanesh, A. Endo, R.Karvembu. Synthesis, structures and mechanistic pathways of anticancer activity of palladium(II) complexes with indole-3-carbaldehyde thiosemicarbazones. RSC New Journal of Chemistry, 2018, 42, 10818-10832. (IF: 3.069 in 2018)
13. G. Rohini, J. Haribabu, M.M. Sheeba, K. N. A. Rahman, N. S. P. Bhuvanesh, C. Balachandran, R. Karvembu, A. Sreekanth. Ru(II)-η6-arene complexes of dibenzosuberenyl appended aroyl/acylthiourea ligands: In vitro biomolecular interaction studies and catalytic transfer hydrogenation. ChemistrySelect, 2018, 3, 12077–12087. (IF: 1.716 in 2018)
14. C. Balachandran, Y. Arun, B. Sangeetha, V. Duraipandiyan, S. Awale, N. Emi, S. Ignacimuthu, P.T. Perumal. In vitro and in vivo anticancer activity of 2-acetyl-benzylamine isolated from Adhatoda vasica L. leaves. Biomedicine & Pharmacotherapy, 2017, 93, 796-806. (IF: 3.743 in 2018)
15. N. Sudhapriya, C. Balachandran, S. Awale, P. T. Perumal. Sn(II)-mediated facile approach for the synthesis of 2-aryl-2H-indazole-3-phosphonates and their anticancer activity. RSC New Journal of Chemistry, 2017, 41, 5582-5594. (IF: 3.069 in 2018)
16. K. Jeyalakshmi, J. Haribabu, C. Balachandran, N. S. P. Bhuvanesh N. Emi, R. Karvembu. Synthesis of Ru(II)-benzene complexes containing aroylthiourea ligand, and their binding with biomolecules and in vitro cytotoxicity through apoptosis. RSC New Journal of Chemistry, 2017, 41, 2672-2686. (IF: 3.069 in 2018)
17. S. Awale, A. M. Tawila, D. F. Dibwe, J. Ueda, S. Sun, S. Athikomkulchai, C. Balachandran, I. Saiki, K. Matsumoto, H. Esumi. Highly oxygenated antiausterity agents from the leaves of Uvaria dac. Bioorganic & Medicinal Chemistry Letters, 2017, 27, 1967–1971. (IF: 2.448 in 2018)
18. D. F. Dibwe, S. Sun, J. Ueda, C. Balachandran, K. Matsumoto, S. Awale. Discovery of potential antiausterity agents from the Japanese cypress Chamaecyparis obtuse. Bioorganic & Medicinal Chemistry Letters, 2017, 27, 4898-4903. (IF: 2.448 in 2018)
19. S. Mayakrishnan, Y. Arun, C. Balachandran, S. Awale, N. U. Maheswari and P. T. Perumal. Ru(II)-catalysed regiospecific C-H/O-H oxidative annulation to access isochromeno[8,1-ab]phenazines: far red fluorescence and live cancer cell imaging. ACS Omega, 2017, 2, 2694−2705. Editor Choice, (IF: 2.584 in 2018)
20. A. Rahman K. N., J. Haribabu, C. Balachandran, N. S. P. Bhuvanesh, R. Karvembu, A. Sreekanth. Copper, nickel and zinc complexes of 3-acetyl coumarin thiosemicarbazone: synthesis, characterization and in vitro evaluation of cytotoxicity and DNA/Protien binding properties. Polyhedron, 2017, 135, 26–35. (IF: 2.284 in 2018)
21. P. Mahendran, A. J. Rajendran, C. Balachandran, A. Stalin, S. Rangan, L. Kothandapani, C. R. Kella, S. Awale, B.N. Hitesh Kumar. Synthesis of novel β-amino alcohols from phenylacetylcarbinol - cytotoxicity activity against A549 cells and molecular docking. Research on Chemical Intermediates, 2017, 1-18. (IF: 2.064 in 2018)
22. M. K. Yuvapriya, P. Selvakumar, C. Balachandran. Novel synthetic unnatural beta amino acids via acid hydrolysis of diazepinones as synthons for antibiotics. American Journal of Pharmtech Research, 2017, 7.
23. C. Balachandran, K. C. Rao, Y. Arun, N. Emi, N. Yamamoto, Y. Inaguma, A. Okamoto, P.T. Perumal. Synthetic investigation on chirally pure Mannich derivatives of pseudophenylpropanolamine and their anticancer properties against HepG-2 cells with inhibition of JAK2/STAT3. RSC Advances, 2016, 6, 96946-96962. (IF: 3.049 in 2018)
24. C. Balachandran, N. Emi, Y. Arun, N. Yamamoto, V. Duraipandiyan, Y. Inaguma, A. Okamoto, S. Ignacimuthu, N.A. Al-Dhabi, P.T. Perumal. In vitro antiproliferative activity of 2,3-dihydroxy-9,10-anthraquinone induced apoptosis against COLO320 cells through cytochrome c release caspase mediated pathway with PI3K/AKT and COX-2 inhibition. Chemico-Biological Interaction, 2016, 249, 23-35. (IF: 3.407 in 2018)
25. C. Balachandran, V. Duraipandiyan, Y. Arun, B. Sangeetha, N. Emi, N.A. Al-Dhabi, S.Ignacimuthu, Y. Inaguma, A. Okamoto, P. T. Perumal. Isolation and characterization of 2-hydroxy-9,10-anthraquinone from Streptomyces olivochromogenes (ERINLG-261) with antimicrobial, cytotoxic and molecular docking properties. Brazilian Journal of Pharmacology, 2016, 26, 285–295. (IF: 1.754 in 2018)
26. S. Mayakrishnan, Y. Arun, C. Balachandran, N. Emi, D. Muralidharan, P. T. Perumal. Synthesis of cinnolines via Rh(III)-catalysed dehydrogenative CH/N-H functionalization: Aggregation induced emission and cell imaging. Organic & Biomolecular Chemistry, 2016, 14, 1958-1968. (IF: 3.49 in 2018)
27. K. Parthasarathy, C. Praveen, K. Saranraj, C. Balachandran, P. S. Kumar. Synthesis, antimicrobial and cytotoxic evaluation of spirooxindole [pyrano-bis-2H-l-benzopyrans]. Medicinal Chemistry Research, 2016, 25, 2155–2170. (IF: 1.72 in 2018)
28. C. Balachandran, N. Emi, Y. Arun, Y. Yamamoto, B. Ahilan, B. Sangeetha, V. Duraipandiyan, Y. Inaguma, A. Okamoto, S. Ignacimuthu, N.A. Al- Dhabi, P.T. Perumal. In vitro anticancer activity of methyl caffeate isolated from Solanum torvum Swartz. fruit. Chemico-Biological Interaction, 2015, 242, 81-90. (IF: 3.407 in 2018) Most downloaded article-October To December 2015
29. C. Balachandran, P. S. Kumar, Y. Arun, V. Duraipandiyan, R. L. Sundaram, A. Vijayakumar, K. Balakrishna, S. Ignacimuthu, N. A. Al-Dhabi, P.T. Perumal. Antimicrobial, antioxidant, cytotoxic and molecular docking properties of N-benzyl-2,2,2-trifluoroacetamide. Applied Nanoscience, 2015, 5, 207–216. (IF: 3.198 in 2018)
30. C. Balachandran, V. Duraipandiyan, N. A. Al-Dhabi, A. Stalin, K. Balakrishna, S. Ignacimuthu, F. Tilton. Isolation and characterization of anthraquinone from Streptomyces sp. ERINLG-26 with anticancer activity against adenocarcinoma cell line COLO320. Applied Biochemistry and Microbiology, 2015, 51, 522–529. (IF: 0.727 in 2018)
31. C. Balachandran, V. Duraipandiyan, N. Emi, S. Ignacimuthu. Antimicrobial and cytotoxic properties of Streptomyces sp. (ERINLG-51) isolated from Southern Western Ghats. South Indian Journal of Biological sciences, 2015, 7-14.
32. K. Easwaramoorthy, A. Jeya Rajendran, K. Chennakesava Rao, Y. Arun, C. Balachandran, M. Govindan, T. Prakasam, P. T. Perumal, and Nobuhiko Emi. Synthesis of Novel 1,4-Disubstituted 1,2,3-Triazolo-Bosentan Derivatives – Evaluation of Antimicrobial, Anticancer activities and Molecular Docking. RSC Advances, 2015, 5, 105266. (IF: 3.049 in 2018)
33. N. Sudhapriya, A. Nandakumar, Y Arun, P.T. Perumal, C. Balachandran, N. Emi . An Expedient Route to Highly Diversified [1,2,3]Triazolo[1,5-a][1,4]Benzodiazepines and their Evaluation for Antimicrobial, Antiproliferative and In Silico studies. RSC Advances, 2015, 5, 66260-66270. (IF: 3.049 in 2018)
34. K. Parthasarathy, C. Praveen, P. Senthil Kumar, C. Balachandran, P. T. Perumal. Cu(OTf)2 catalyzed three component strategy for the synthesis of thienopyridine containing spirooxindoles and their cytotoxic evaluation. RSC Advances, 2015, 5, 15818-15830. (IF: 3.049 in 2018)
35. K. Chennakesava Rao, K. Easwaramoorthi, Y. Arun, C. Balachandran, K.S. Muralidhara Rao, Govindhan M, N. Emi, T. Prakasam and P.T. Perumal. Synthesis of BF3 catalyzed Mannich derivatives with excellent ee from phenylpropanolamine, study of their antimicrobial activity and molecular docking. Bioorganic & Medicinal Chemistry Letters, 2015, 25, 4232–4238. (IF: 2.448 in 2018)
36. S. S. Sulthana, S. A. Antony, C. Balachandran, S. S. Shafi. Thiophene and benzodioxole appended thiazolyl-pyrazoline compounds: Microwave assisted synthesis, antimicrobial and molecular docking studies. Bioorganic & Medicinal Chemistry Letters, 2015, 25, 2753–2757. (IF: 2.448 in 2018)
37. P. S. Kumar, C. Balachandran, V. Duraipandiyan, D. Ramasamy, S. Ignacimuthu. Extracellular biosynthesis of silver nanoparticle using Streptomyces sp. 09 PBT 005 and its antibacterial and cytotoxic properties. Applied Nanoscience, 2015, 5, 169–180. (IF: 3.198 in 2018)
38. C. Balachandran, B. Sangeetha, V. Duraipandiyan, M. Karunai Raj, S. Ignacimuthu, N.A. Al-Dhabi, K. Balakrishna, K. Parthasarathy, N.M. Arulmozhi, M. Valan Arasu. A flavonoid isolated from Streptomyces sp. (ERINLG-4) induces apoptosis in human lung cancer A549 cells through p53 and cytochrome c release caspase-dependant pathway. Chemico-Biological Interaction, 2014, 224, 24–35. (IF: 3.407 in 2018) Most downloaded article-October To December 2014
39. C. Balachandran, Y. Arun, V. Duraipandiyan, S. Ignacimuthu, K. Balakrishna, N.A. Al-Dhabi. Antimicrobial and cytotoxicity properties of 2,3-dihydroxy-9,10-anthraquinone isolated from Streptomyces galbus (ERINLG-127). Applied Biochemistry and Biotechnology, 2014, 172, 3513-3528. (IF: 2.14 in 2018)
40. C. Balachandran, V. Duraipandiyan, M. V. Arasu, S. Ignacimuthu. Antimicrobial, antioxidant and cytotoxic properties of Streptomyces sp. (ERINLG-01) isolated from Southern Western Ghats. International Journal of Pharmacy & Pharmaceutical Sciences, 2014, 6, 189-196.
41. Y. Arun, K. Saranraj, C. Balachandran, P. T. Perumal. Novel spirooxindole-pyrrolidine compounds: Synthesis, anticancer and molecular docking studies. European Journal of Medicinal Chemistry, 2014, 74, 50-64. (IF: 4.833 in 2018). Most downloaded articles; January To March 2014
42. N. Sudhapriya, P.T. Perumal, C. Balachandran, S. Ignacimuthu, M. Sangeetha, Mukesh Doble. Synthesis of new class of spirocarbocycle derivatives by multicomponent domino reaction and their evaluation for antimicrobial, anticancer activity and Molecular docking studies. European Journal of Medicinal Chemistry, 2014, 83, 190-207. (IF: 4.833 in 2018)
43. K. Chennakesava Rao, Y. Arun, K. Eswaramoorthi, C. Balachandran, T. Prakasam, T. Eswara Yuvaraj, P.T. Perumal. Synthesis, antimicrobial and molecular docking studies of enantiomerically pure N-alkylated β-amino alcohols from phenylpropanolamines. Bioorganic & Medicinal Chemistry Letters, 2014, 24, 3057–3063. (IF: 2.448 in 2018)
44. P. S. Kumar, N.A. Al-Dhabi, V. Duraipandiyan, C. Balachandran, P. P. Kumar and S. Ignacimuthu. In vitro antimicrobial, antioxidant and cytotoxic properties of Streptomyces lavendulae strain SCA5. BMC Microbiology, 2014, 14, 291. (IF: 3.287 in 2018)
45. D. Kathirvelan, J. Haribabu, BSR Reddy, C. Balachandran and V. Duraipandiyan. Facile and diastereo selective synthesis of 3,2'-spiropyrrolidine-oxindoles derivatives, their molecular docking and antiproliferative activities. Bioorganic & Medicinal Chemistry Letters, 2014, 25, 389-399. (IF: 2.448 in 2018)
46. A. Vijayakumar, B. Jeyaraj, M. Karunai Raj, I.V.S. N. Christhudas, C. Balachandran, P. Agastian, S. Ignacimuthu. In vitro cytotoxicity, α-glucosidase inhibition, antioxidant and free radical scavenging activities of Illicium griffithii Hook. f. & Thoms fruits. Medicinal chemistry Research, 2014, 23, 2769 – 2779. (IF: 1.72 in 2018)
47. V. Duraipandiyan, N.A. AL-Dhabi, C. Balachandran, M. Karunai Raj, M. Valan Arasu, S. Ignacimuthu. Novel 1, 5, 7- trihydroxy-3-hydroxy methyl anthraquinone isolated from terrestrial Streptomyces sp. (ERI-26) with antimicrobial and molecular docking studies. Applied Biochemistry and Biotechnology, 2014,174, 1784-1794. (IF: 2.14 in 2018)
48. L. Palanikumar, S. Ramasamy, C. Balachandran. Size dependent antimicrobial response of zinc oxide 1 nanoparticles. IET Nanobiotechnology, 2014, 8,111-117. (IF: 1.925 in 2018)
49. V. Duraipandiyan, N. A. Al-Dhabi, C. Balachandran, S. Ignacimuthu, C. Sankar, and K. Balakrishna. Antioxidant and cytotoxic properties of Vasicine acetate synthesized from Vasicine isolated from Adhatoda vasica L. BioMed Research International, 2014, Article ID 727304. (IF: 2.197 in 2018)
50. Selvarangam E. Kiruthika, P. T. Perumal, C. Balachandran, S. Ignacimuthu. An easy protocol for the domino synthesis of diversely functionalized spirocarbocycles and their biological evaluation. Journal of Chemical sciences, 2014, 126, 177-185. (IF: 1.496 in 2018)
51. G. Nattudurai, C. Balachandran, M. G. Paulraj, V. Duraipandiyan, S. Ignacimuthu, N. A. Al-Dhabi. Cytotoxic and antioxidant properties of fractions isolated from Feronia elephantum. International Journal of Pharmacy & Pharmaceutical Sciences, 2014, 6, 210-214.
52. C. Balachandran, V. Duraipandiyan, K. Balakrishna, R. L. Sundaram, A. Vijayakumar, S. Ignacimuthu, Naif Abdullah Al-Harbi. Synthesis and medicinal properties of plant-derived vilangin. Environmental Chemistry Letters, 2013, 11, 303-308. (IF: 4.617 in 2018)
53. L. Palanikumar, S. Ramasamy, G. Hariharan, C. Balachandran. Influence of particle size of nano zinc oxide on the controlled delivery of Amoxicillin. Applied Nanoscience. 2013, 3, 441–451. (IF: 3.198 in 2018)
54. Y. Arun, G. Bhaskar, C. Balachandran, S. Ignacimuthu, P.T. Perumal. Facile one-pot synthesis of novel dispirooxindole-pyrrolidine derivatives and their antimicrobial and anticancer activity against A549 human lung adenocarcinoma cancer cell line. Bioorganic & Medicinal Chemistry Letters, 2013, 23, 1839–1845. (IF: 2.448 in 2018)
55. K. Parthasarathy, C. Praveen, C. Balachandran, P. Senthil kumar, S. Ignacimuthu, P.T. Perumal. Cu(OTf)2 catalyzed three component reaction: Efficient synthesis of spiro[indoline-3,4’-pyrano[3,2-b]pyran derivatives and their anticancer potency towards A549 human lung cancer cell lines. Bioorganic & Medicinal Chemistry Letters, 2013, 23, 2708–2713. (IF: 2.448 in 2018)
56. L. Palanikumar, S. Ramasamy, C. Balachandran. Antibacterial and cytotoxic response of nano zinc oxide in gram negative bacteria and COLO320 human adenocarcinoma cancer cells. Current Nanoscience, 2013, 9, 469-478. (IF: 1.58 in 2018)
57. C. Balachandran, V. Duraipandiyan, K. Balakrishna, S. Ignacimuthu. Petroleum and polycyclic aromatic hydrocarbons (PAHs) degradation and naphthalene metabolism in Streptomyces sp. (ERI-CPDA-1) isolated from oil contaminated soil. Bioresource Technology, 2012,112, 83–90. (IF: 6.669 in 2018)
58. C. Balachandran, V. Duraipandiyan, N. A. Al-Dhabi, K. Balakrishna, N. P. Kalia, V. S. Rajput, I. A.Khan, S. Ignacimuthu. Antimicrobial and Antimycobacterial Activities of Methyl Caffeate Isolated from Solanum torvum Swartz. Fruit. Indian Journal of Microbiology, 2012, 52, 676–681. (IF: 1.533 in 2018)
59. C. Balachandran, V. Duraipandiyan, S. Ignacimuthu. Purification and characterization of protease enzyme from actinomycetes and its cytotoxic effect on cancer cell line (A549). Asian Pacific Journal of Tropical Biomedicine, 2012, S392-S400.
60. C. Balachandran, V. Duraipandiyan, S. Ignacimuthu. Cytotoxic (A549) and antimicrobial effects of Methylobacterium sp. isolate (ERI-135) from Nilgiris forest soil, India. Asian Pacific Journal of Tropical Biomedicine, 2012, 712-716.
61. G. Bhaskar, Y. Arun, C. Balachandran, C. Saikumar, P. T. Perumal. Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity. European Journal of Medicinal Chemistry, 2012, 51, 79-91. (IF: 4.833 in 2018) Most downloaded articles January To December 2012.
62. M. Karunai Raj, C. Balachandran, V. Duraipandiyan, P. Agastian, S. Ignacimuthu. Antimicrobial activity of Ulopterol isolated from Toddalia asiatica (L.) Lam.:A traditional medicinal plant. Journal of Ethnopharmacology, 2012, 140, 161– 165. (IF: 3.414 in 2018)
63. N. A. Al-Harbi, C. Balachandran, M. Karunai Raj, V. Duraipandiyan, C. Muthukumar, S. Ignacimuthu, Inshad Ali Khan. Antimicrobial, antimycobacterial and antibiofilm properties of Couroupita guianensis Aubl. fruit extract. BMC Complementary and Alternative Medicine, 2012, 12, 242. (IF: 2.479 in 2018)
64. M. Karunai Raj, C. Balachandran, V. Duraipandiyan, P. Agastian, S. Ignacimuthu, I. A. Khan.. Isolation of terrestribisamide from Peltophorum pterocarpum (DC.) Baker ex. K. Heyne and its antimicrobial, antioxidant, and cytotoxic activities. Medicinal chemistry Research, 2012, 22, 3823-3830. (IF: 1.72 in 2018)

1. THE ICHIRO KANEHARA FOUNDATION scholarship for Foreign Nationals in Japan. (Year 2015-April to 2016-March). Department of Hematology, Fujita Health University, Dengakugakubo, Kutsukake Toyoake, Aichi, Japan.

Naif Abdullah Al-Dhabi, Savarimuthu Ignacimuthu, C. Balachandran, Veeramuthu Duraipandiyan. Process for obtaining a naphthoquinone derivative from Streptomyces sp. (USA: US 10,036,048 B1. Date: 31/07/2018).

The Pharmaceutical Society of Japan, 2018-2020.

1. Balachandran, C., Duraipandiyan, V., and Ignacimuthu, S. Partial digestion of 16s r RNA of Streptomyces sp., from soil samples, Nilgiris, Western Ghats of Tamil Nadu, Division of Microbiology, Entomology Research Institute, Loyola College, Chennai, 600034, India. Accession Number- KF061084 to KF061093 (Total 10).
2. Balachandran, C., Duraipandiyan, V., and Ignacimuthu, S. Partial digestion of 16s r RNA of Streptomyces sp., from soil samples, Nilgiris, Western Ghats of Tamil Nadu, Division of Microbiology, Entomology Research Institute, Loyola College, Chennai, 600034, India. Accession Number - KF006404 to KF006410 (Total 7).
3. Balachandran, C., Duraipandiyan, V., Valan Arasu, M., Ignacimuthu, S. and Kinsalin, V.A. Partial digestion of 16s r RNA of Streptomyces sp., from soil samples, Nilgiris, Western Ghats of Tamil Nadu, India. Division of Microbiology, Entomology Research Institute, Loyola College, Chennai, 600034, India. Accession Number - HQ385920 and HQ385921.
4. Balachandran, C., Duraipandiyan, V., and Ignacimuthu, S. Partial digestion of 16s r RNA of Streptomyces sp., from soil samples, Nilgiris, Western Ghats of Tamil Nadu, Division of Microbiology, Entomology Research Institute, Loyola College, Chennai, 600034, India. Accession Number -KC820653 and KC820652.
5. Balachandran, C., Host Antony David, R., Duraipandiyan, V., and Ignacimuthu, S. Partial digestion of 16s r RNA of Streptomyces sp. from soil samples, Nilgiris, Western Ghats of Tamil Nadu, Division of Microbiology, Entomology Research Institute, Loyola College, Chennai, Tamil Nadu 600034, India. Accession Number -KC710245 and KC710246.
6. Balachandran, C., Host Antony David, R., Duraipandiyan, V., and Ignacimuthu, S. Partial digestion of 16s r RNA of Streptomyces sp. ERINLG-201 from Mudumalai forest soil, Nilgiris, Western Ghats of Tamil Nadu, Division of Microbiology, Entomology Research Institute, Loyola College, Chennai, Tamil Nadu 600034, India. Accession Number -KC820651.
7. Balachandran, C., Duraipandiyan, V., Valan Arasu, M., and Ignacimuthu, S. Partial digestion of 16s r RNA of Streptomyces sp. ERI-CPDA-1. Division of Microbiology, Entomology Research Institute, Loyola College, Chennai, 600034, India. Accession Number -HQ385919.
8. Balachandran, C., Duraipandiyan, V., and Ignacimuthu, S. Partial digestion of 16s r RNA of Methylobacterium sp. ERI-135 from Doddabetta forest soil, Nilgiris, Western Ghats of Tamil Nadu, Division of Microbiology, Entomology Research Institute, Loyola College, Chennai, 600034, India. Accession Number - JQ350893.
9. Balachandran, C., Duraipandiyan, V., and Ignacimuthu, S. Partial digestion of 16s r RNA of Streptomyces sp. ERI-INS-009 from Doddabetta forest soil, Nilgiris, Western Ghats of Tamil Nadu, Division of Microbiology, Entomology Research Institute, Loyola College, Chennai, 600034, India. Accession Number -KF732808.

1. C. Balachandran, Kenta Yokoi, Kana Naito, Shin Aoki. Mechanistic Study of Cell Death of Cancer Cells Induced by Cyclometalated Iridium(III)-Peptide Hybrids (IPHs). The 139th Annual Meeting of the Pharmaceutical Society of Japan, March 21~23, 2019 at Makuhari-Messe, Japan. (Oral Presentation).
2. C. Balachandran, Kenta Yokoi, Kana Naito, Shin Aoki. Mechanistic Study of Cell Death of Cancer Cells Induced by Cyclometalated Iridium(III)-Peptide Hybrids (IPHs). Symposium of “Division of Medical-Science-Engineering Cooperation” in the Research Institute for Science and Technology, Held at Tokyo University of Science, Japan, 22/12/2018 (Poster Presentation).
3. C. Balachandran, Kenta Yokoi, Kana Naito, Shin Aoki. Cyclometalated Iridium(III)-Peptide Hybrids (IPHs) Inducing Paraptosis Mediated Cell Death in Human Jurkat Cells. International Symposium of Tokyo University of Science, Translational Research (TR) center-Frontiers in Developmental Strategy for Cancer Therapeutics. Held at Tokyo University of Science, Japan, 20/10/2018 (Poster Presentation)
4. C. Balachandran, Dya Fita Dibwe, Suresh Awale. Antiausterity activity of isopanduratin-A and its mechanism of action against PANC-1 human pancreatic cancer cells. The 137th Annual Meeting of the Pharmaceutical Society of Japan, 2018，3/25-28, Kanazawa, Japan. (Oral Presentation)
5. C. Balachandran. Aichi Symposium of Hematology (ASH), Novel agents isolated from natural products with antimicrobial, anticancer and in silico studies. 05-09-2015, Aichi, Japan (Oral Presentation).
6. C. Balachandran, Yukiya Yamamoto, Nobuhiko Emi. ‘Novel Compounds Isolated From Natural Products With Antimicrobial, Anticancer And In Silico Studies’ Department of Hematology, Fujita Health University, Aichi, Japan. Sep 23rd 2015 (Poster Presentation).
7. C. Balachandran, V. Duraipandiyan, K. Balakrishna, S. Ignacimuthu, National conference on “TECHNOLOGY FOR WEALTH FROM WASTE” at 8th and 9th January 2013. Petroleum and polycyclic aromatic hydrocarbons (PAHs) degradation and naphthalene metabolism in Streptomyces sp. (ERI-CPDA-1) isolated from oil contaminated soil. LIFE and LICET. (Oral Presentation)
8. C. Balachandran, V. Duraipandiyan, K. Balakrishna, S. Ignacimuthu. National Seminar on “Role of Microbes in Health, Agriculture and Industry” Department of Biotechnology, Alagappa University, Karaikudi at March 26-27, 2012. (Poster Presentation)
9. Shin Aoki, Kenta Yokoi, C. Balachandran, Haribabu Jebiti, Abdullah-Al Masum, and Kana Naito. Recent Progress in the Design and Synthesis of Cyclometalated Iridium(III) Complexes Based on Post-Complexation Functionalization. 3rd Acian Conference on Chemosensors and Imaging Probes (Asian ChIP-2019), Amritsar, India. 2019-11- 6 to 11-9.
10. Masumi Hirose, C. Balachandran, Zhu Jun Jie, and Shin Aoki. Design and Synthesis of Poly(2,2’-bipyridyl) Ligands and Controlled of Anticancer Activity by Metal Complexation. 7th Asian Congress on Coordination Chemistry (ACCC7). Kuala Lumpur, Malaysia. 2019-10-15 to 10-18
11. Kenta Yokoi, C. Balachandran, and Shin Aoki. Amphiphilic Cationic Triscyclometalated Iridium(III) Complex-Peptide Hybrids Induce Paraptosis-like Cell Death of Cancer Cells via Intracellular Ca2+-Dependent Pathway. 7th Asian Congress on Coordination Chemistry (ACCC7). Kuala Lumpur, Malaysia. 2019-10-15 to 10-18.
12. Shin Aoki, Kenta Yokoi, Kana Naito, C. Balachandran, Ayami Kazama, Junpei YuasaKuroda. Design and Synthesis of Cyclometalated Iridium(III) Complexes Functionalized with Peptides and Chromophores in Biomedical and Material Sciences. The 69th meeting of the Complexation Society. Nagoya City (Nagoya University). 2019-09-21 to 23.
13. Shin Aoki, Kenta Yokoi, Yuichi Tamura, Kana Naito, Ayami Kazama, C. Balachandran, Haribabu Jebiti, Junpei Yuasa, and Reiko Kurod. Selective Substitution and Decomposition Reactions of Cyclometalated Iridium Complexes and Their Applications to Biomedical and Material Sciences. The 27th International Society of Heterocyclic Chemistry Congress (ISHC2019). Kyoto, Japan. 2019-9-1 to 9-6.
14. Shin Aoki, Yuichi Tamura, Hiroki Ohwada, Kenta Yokoi, C. Balachandran, Ayami Kazama, Kyouhei Sato, Reiko Kuroda, Junpei Yuasa. Recent Progress in the Design and Synthesis of Cyclometalated Iridium(III) Complexes Based on Post-Complexation Functionalization. 23th International Symposium on Photochemistry and Photophysics of Coordination Compounds (ISPPCC2019) 2019-7-14 to 7- 19.
15. Shin Aoki, Kenta Yokoi, C. Balachandran, Kana Naito. Programmed cell death induction of cancer cells by cyclometalated Ir (III) complex-peptide hybrid and its mechanism analysis. The 13th Annual Meeting of the Japan Society for Chemical Biology. June 10 to 12, 2019.
16. Shin Aoki, Kenta Yokoi, Kana Naito, C. Balachandran, Shun Shimizu. Design and Synthesis of Cyclometalated Iridium(III) Comple-Peptide Hybrids for th eInduction of Cancer Cell Death. 15th International Symposium of Applied Biological Chemixstry (ISABC15). June 2-5, 2019. Nara, Kasugano International Forum “Iraka”.
17. Kenta Yokoi, C. Balachandran, Kana Naito, Ryo Shimizu, Shin Aoki. Design and synthesis of cyclometalated iridium (Ir (III)) complex basic peptide hybrid. The 17th Organic Chemistry Symposium for the Next Generation, Tokyo, May 31-June 1, 2019.
18. Shin Aoki, Kenta Yokoi, Kana Naito, Kazama Ayami, C. Balachandran. Cell Death Induction of Cancer Cells by Cyclometalated Iridium(III) Complex-Peptide Hybrids and Its Mechanism. 99th annual meeting of Japan Chemical Society, Konan University. March 16 to 18, 2019.
19. Kenta Yokoi, Kana Naito, Masum Abdulah-Al, C. Balachandran, Shin Aoki. Design and Synthesis of Cyclometalated Iridium(III)-Peptide Hybrids (IPHs) Inducing Different Types of Cell Death. International Symposium of Tokyo University of Science, Translational Research (TR) center-Frontiers in Developmental Strategy for Cancer Therapeutics. Held at Tokyo University of Science, Japan, 20/10/2018(Poster Presentation).
20. Sijia Sun, Dya Fita Dibwe, C. Balachandran, Ampai Phrutivorapongkul, Suresh Awale Furanocoumarins from the peels of Citrus hystrix and their antiausterity activity against three human pancreatic cancer cell lines. The 137th Annual Meeting of the Pharmaceutical Society of Japan 2018，3/25-28, Kanazawa, Japan.
21. Dya Fita Dibwe, Nusrin Pongterdsak, Kritsaya Chaithatwatthana, Ampai Phrutivorapongkul, Ahmed M. Tawila, C. Balachandran, Suresh Awale Discovery of potential antiausterity agents from Thai Derris scandens The 137th Annual Meeting of the Pharmaceutical Society of Japan 2018，3/25-28, Kanazawa, Japan.
22. Sijia Sun, Dya Fita Dibwe, C. Balachandran, Ampai Phrutivorapongkul, Suresh Awale Bergamottin, an anti-austerity agent from Citrus hystrix induced autophagy mediated PANC-1 cell death International Symposium on Scientific Research of Traditional Medicine, Nov. 10, 2017, Toyama.
23. Nusrin Pongterdsak, Kristaya Chaithatwatthana, Ampai Phrutivorapongkul, Sijia Sun, Ahmed M. Tawila, Ashraf M. Omar, C. Balachandran, Dya Fita Dibwe, Suresh Awale. Study on the anti-austerity activity of Derris scandens extract against the PANC-1 human pancreatic cancer cell line International Symposium on Scientific Research of Traditional Medicine, Nov. 10, 2017, Toyama.
24. Kristaya Chaithatwatthana, Nusrin Pongterdsak, Ampai Phrutivorapongkul, Sijia Sun, Ashraf M. Omar, Ahmed M. Tawila, C. Balachandran, Dya Fita Dibwe, Suresh Awale. Anti-austerity activity of Piper betleextract against the PANC-1 human pancreatic cancer cell line International Symposium on Scientific Research of Traditional Medicine, Nov. 10, 2017, Toyama.
25. Takahiro Maruyama, Takahiro Okada, Takuya Okada, Satoyuki Takahara, C. Balachandran, Dya Fita Dibwe, Suresh Awale, Naoki Toyooka, Synthesis and evaluation of preferential cytotoxicity under nutrient-deprived conditions of plumbagin derivatives. The 35th Medicinal Chemistry Symposium, Oct. 25-27, 2017, Nagoya.
26. Sijia Sun, Dya Fita Dibwe, C. Balachandran, Ampai Phrutivorapongkul, Suresh Awale. Discovery of antiausterity strategy based anticancer agents from Citrushystrix DC. Toyama Academic GALA 2017, Sept. 27, Toyama.
27. C. Balachandran. Toyoake Hematology Seminar- ‘Frontline Treatment in Transplant-Ineligible Multiple Myeloma 29/7/2016, Fujita Health University, Japan.
28. C. Balachandran. The 13th Tokai Slide conference of Leukemia, 12/09/2015, Nagoya, Japan.
29. Y. Arun, C. Balachandran, P.T. Perumal. ‘Synthesis, anticancer and molecular Docking studies of novel spirooxindole pyrrolidine compounds’ 15th Tetrahedron Symposium, Challenges in Bioorganic and Organic Medical Chemistry, London, UK, 24-27 June 2014.

住所

千葉県野田市山崎２６４１　15号館　5F

電話番号

04-7124-1501（内線：6542）