職歴
53. Goitsuka, R., Chen, C-L., and Cooper, MD.1997. B cells in the Bursa of Fabricius express a novel C-type lectin gene. J. Immunol. 159:3126-3132.

54. Momoi, Y., Okai, Y., Watari, T., Goitsuka, R., Tsujimoto, H., and Hasegawa, A.1998. Establishment and characterization of a canine T-lymphoid cell line derived from malignant lymphoma. Vet. Immunol. Immunopathol. 59:11-20.

55. Goitsuka, R., Fujimura, Y., Mamada, H., Umeda, A., Morimura, T., Uetsuka, K., Doi, K., Tsuji, S., and Kitamura, D. 1998. BASH, a novel signalling molecule preferentially expressed in B cells of the bursa of Fabricius. J. Immunol. 161: 5804-5808.

56. Goitsuka, R., Hayashi, N., Nagase, M., Sasaki, N., Ra, C., Tsujimoto, H., and Hasegawa, A. 1999. Molecular cloning of cDNAs encoding canine high-affinity IgE receptor ?, ?, and ?-chains. Immunogenetics 49: 580-582.

57. Hayashi, K., Nittono R., Okamoto, N., Kawahara, S., Hara, Y., Goitsuka ,R., and Kitamura, D. 2000. B cell-restricted adaptor BASH is required for normal development and antigen receptor-mediated activation of B cells. Proc. Natl. Acad. Sci. USA 97:2755-2760.

58. Goitsuka, R., Kanazashi, H., Sasanuma, H., Fujimura, Y., Hidaka, Y., Tatsuno, A., Ra, C., Hayashi, K., and Kitamura D. 2000. A BASH/SLP-76-related adaptor protein MIST/Clnk involved in IgE receptor-mediated degranulation. Int. Immunol. 12: 573-580.

59. Fusaki, N., Tomita, S., Wu, Y., Okamoto, N., Goitsuka, R., Kitamura, D., and Hozumi, N. 2000. BLNK is associated with the CD72/SHP-1/Grb2 complex in the WEHI231` cell line after membrane IgM cross-linking. Eur. J. Immunol., 30:1326-1330.

60. Morimura, T., Goitsuka, R., Zhang, Y., Saito, I., Reth, M., and Kitamura, D. 2001. Cell cycle arrest and apoptosis induced by Notch1 in B cells. J. Biol. Chem. 275:36523-36531.

61. Morimura, T., Miyatani, S., Kitamura, D., and Goitsuka, R. 2001. Notch signaling suppresses IgH gene expression in chicken B cells: implication in spatially restricted expression of Serrate2/Notch1 in the bursa of Fabricius. J. Immunol. 166:3277-3283.

62. Goitsuka, R., Mamada, H., Kitamura, D., Cooper, M. D., and Chen, C-L, H. 2001. Genomic structure and transcriptional regulation of the early B cell gene chB1. J. Immunol. 167:1454-1460.

63. Tsuji, S., Okamoto, M., Yamada, K., Okamoto, N., Goitsuka, R., Arnold, R., Kiefer, F., and Kitamura, D. 2001. B cell adaptor containing Src homology 2 domain (BASH) links B cell receptor signaling to the activation of hematopoietic progenitor kinase 1. J. Exp. Med. 194:529-539.

64. Goitsuka, R., Tatsuno, A., Ishiai, M., Kurosaki, T., and Kitamura, D. 2001. MIST functions through distinct domains in immunoreceptor signaling in the presence and absence of LAT. J. Biol. Chem. 276:36043-36050.

65. Hayashi K, Kobayashi T, Umino T, Goitsuka R, Matsui Y, and Kitamura D. 2002. SMAD1 signaling is critical for initial commitment of germ cell lineage from mouse epiblast. Mech. Dev.118:99-109.

66. Caprioli A, Goitsuka R, Pouget C, Dunon D, and Jaffredo T. 2002. Expression of Notch genes and their ligands during gastrulation in the chicken embryo. Mech. Dev. 116:161-164.

67. Fujii, Y., Wakahara, S., Nakao, T., Hara, T., Ohtake, H., Komurasaki, T., Kitamura, K., Tatsuno, A., Fujiwara, N., Hozumi, N., Ra, C., Kitamura, D., and Goitsuka, R. 2003. Targeting of MIST to Src-family kinases via SKAP55-SLAP-130 adaptor complex in mast cells. FEBS Letters 540:111-116.

68. Hayashi, K., Yamamoto, M., Nojima, T., Goitsuka, R. and Kitamura, K. 2003. Distinct signaling requirements for Dm selection, IgH allelic exclusion, pre-B cell transition, and tumor suppression in B cell progenitors. Immunity 18: 825-836.

69. Sasanuma, H., Tatsuno, A., Tsuji, K., Hidano, S., Kitamura, T., Kuno, M., Kitamura, D. and Goitsuka, R. 2004. Transcriptional regulation of SLP-76 family hematopoietic cell adaptor MIST/Clnk by STAT5. Biochem.Biophys.Res.Comm.321:145-153.

70. Hayashi, K., Nojima, T., Goitsuka R., Kitamura, D. 2004.Impaired receptor editing in the primary B cell repertoire of BASH-deficient mice. J. Immunol.173:5980-5988.

71. Yamamoto, M., Nojima, T., Hayashi, K., Goitsuka, R., Furukawa, K., Azuma, T., Kitamura, D. 2004. BASH-deficient mice: limited primary repertoire and antibody formation, but sufficient affinity maturation and memory B cell generation, in anti-NP response. Int. Immunol.16:1161-1171.

72. Nishida, K., Yamasaki, S., Ito, Y., Kabu, K., Hattori, K., Tezuka, T., Nishizumi, H., Kitamura, D., Goitsuka, R., Geha, R. S., Yamamoto, T., Yagi, T., Hirano, T. FceRI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane. J. Cell. Biol. 2005.170:115-126.

73. Oshiumi, H., Shida, K., Goitsuka, R., Kimura, Y., Katoh, J., Ohba, S., Tamaki, Y., Hattori, T., Yamada, N., Inoue, N., Matsumoto, M., Mizuno, S., Seya, T. Regulator of Complement Activation (RCA) Locus in Chicken: Identification of Chicken RCA Gene Cluster and Functional RCA Proteins. J. Immunol. 2005.175:1724-1734.

74. Sasanuma, H., Tatsuno, A., Hidano, S., Ohshima, K., Matsuzaki, Y., Hayashi, K., Lowell, C. A., Kitamura, D. and Goitsuka, R.: Dual  function for the adaptor MIST in IFN-γ production by NK and CD4+NKT ncells regulated by the Src-kinase Fgr. Blood in press.

75. Nojima, T., Hayashi, K., Goitsuka, R., Nakayama, K., Nakayama, K.-i. and Kitamura, D.: Double knockout mice show BASH and PKCδ have different epistatic relationships in B cell maturation and CD40-mediated activation. Immunol. Lett. in press.


※1〜52の論文(生命研所属以前の論文)は割愛させていただきました。

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