:root {
  color-scheme: light;
  --ink: #273447;
  --navy: #293f60;
  --muted: #566273;
  --rule: #dce1e7;
}

* { box-sizing: border-box; }
html { -webkit-text-size-adjust: 100%; scrollbar-gutter: stable; }
body {
  margin: 0;
  background: #fff;
  color: var(--ink);
  font-family: "Hiragino Kaku Gothic ProN", "Hiragino Sans", "Yu Gothic", Meiryo, sans-serif;
  font-size: 17px;
  line-height: 1.9;
  overflow-wrap: anywhere;
}
a { color: var(--navy); text-underline-offset: .22em; }
a:hover { text-decoration-thickness: 2px; }
a:focus-visible, summary:focus-visible {
  outline: 3px solid #567da8;
  outline-offset: 5px;
}
.skip-link {
  position: absolute;
  top: 8px;
  left: 16px;
  z-index: 1;
  padding: 8px 16px;
  background: #fff;
  transform: translateY(-180%);
}
.skip-link:focus { transform: none; }
.site-header { border-top: 4px solid var(--navy); border-bottom: 1px solid var(--rule); }
.header-inner, .page-content, .footer-inner {
  width: min(840px, calc(100% - 64px));
  margin-inline: auto;
}
.header-inner {
  display: flex;
  align-items: center;
  justify-content: space-between;
  gap: 24px;
  min-height: 94px;
}
.lab-name { display: block; line-height: 1.65; text-decoration: none; }
.university-name { display: block; font-size: 13px; font-weight: 600; letter-spacing: .04em; }
.laboratory-name { display: block; font-size: 21px; font-weight: 700; letter-spacing: .05em; }
.home-link { font-size: 13px; color: var(--muted); text-decoration: none; }
.mobile-home { display: none; }
.introduction { padding-top: 48px; padding-bottom: 37px; }
.eyebrow { margin: 0 0 12px; color: var(--navy); font-size: 15px; font-weight: 600; }
h1 { margin: 0 0 24px; color: var(--navy); font-size: clamp(29px, 4vw, 42px); line-height: 1.5; letter-spacing: .025em; font-weight: 700; }
.lead { margin: 0; font-size: 18px; line-height: 1.9; }
.welcome { margin: 13px 0 0; color: var(--muted); font-size: 16px; }
.provide-action { margin-top: 29px; }
.provide-button {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  gap: 30px;
  min-height: 58px;
  padding: 12px 25px;
  border: 1px solid var(--navy);
  border-radius: 3px;
  background: var(--navy);
  color: #fff;
  font-size: 19px;
  font-weight: 600;
  line-height: 1.5;
  text-decoration: none;
}
.provide-button:hover { background: #1e304b; border-color: #1e304b; }
.simple-guide { margin: 17px 0 0; font-size: 15px; line-height: 1.9; }
.scope-section, .conditions-section { border-top: 1px solid var(--rule); padding: 24px 0; }
h2 { margin: 0 0 9px; color: var(--ink); font-size: 18px; font-weight: 700; line-height: 1.6; }
.scope-section p { margin: 0; font-size: 16px; }
.scope-section p + p { margin-top: 9px; }
.conditions-list { margin: 0; padding-left: 1.25em; font-size: 15px; }
.conditions-list li + li { margin-top: 6px; }
.use-details { margin-top: 15px; font-size: 15px; }
.use-details summary { width: fit-content; padding-block: 6px; color: var(--navy); cursor: pointer; text-decoration: underline; text-underline-offset: .22em; }
.use-details summary:hover { text-decoration-thickness: 2px; }
.details-body { margin-top: 10px; padding: 2px 18px; border-left: 2px solid var(--rule); color: var(--muted); }
.details-body p { margin: 12px 0; }
.safety-note { margin: 14px 0 0; color: var(--muted); font-size: 13px; }
.site-footer { margin-top: 12px; border-top: 1px solid var(--rule); background: #f6f7f9; }
.footer-inner { padding: 25px 0 27px; }
.contact-label { margin: 0 0 5px; color: var(--muted); font-size: 12px; }
.contact-person { margin: 0; font-size: 15px; }
.contact-person span { font-size: 13px; }
.contact-email { margin: 4px 0 0; font-size: 15px; }
.affiliation { margin: 14px 0 0; color: var(--muted); font-size: 12px; }

@media (max-width: 600px) {
  .header-inner, .page-content, .footer-inner { width: calc(100% - 40px); }
  .header-inner { min-height: 83px; gap: 12px; }
  .home-link { font-size: 12px; white-space: nowrap; text-align: right; }
  .desktop-home { display: none; }
  .mobile-home { display: inline; }
  .laboratory-name { font-size: 19px; }
  .introduction { padding-top: 30px; padding-bottom: 28px; }
  .eyebrow { font-size: 13px; margin-bottom: 10px; }
  h1 { font-size: clamp(25px, 7.4vw, 32px); margin-bottom: 19px; letter-spacing: 0; }
  .lead { font-size: 16px; }
  .desktop-break { display: none; }
  .welcome { font-size: 14px; margin-top: 11px; }
  .provide-action { margin-top: 24px; }
  .provide-button { width: 100%; min-height: 56px; font-size: 18px; padding-inline: 16px; gap: 24px; }
  .simple-guide { font-size: 14px; }
  .scope-section, .conditions-section { padding-block: 22px; }
  .scope-section p { font-size: 15px; }
  .contact-person span { display: block; }
  .affiliation { line-height: 1.8; }
}

@media print {
  .site-header { border-top: 0; }
  .home-link, .skip-link { display: none; }
  .header-inner, .page-content, .footer-inner { width: 100%; }
  .introduction { padding-top: 20px; }
  .provide-button { background: #fff; color: #000; }
  .site-footer { background: #fff; }
}